Share link: Event: Special seminar
Registrations closing date: 2018-03-27
This Event is Free!
Please join us for a special seminar on Wednesday, March 28th, in the DeGrandpre Communication Center at 1PM:
"Brain Imaging and Genetics in Autism”
Richard Bethlehem, PhD
Brief bio: Dr Bethlehem is currently a Research Associate at the Autism Research Centre and collaborates with the Geschwind lab at UCLA to work on integrated Neuroimaging and Transcriptomics in order to gain better understanding of genetic underpinnings of atypical neurodevelopment. His work is funded by the Autism Research Trust, Marmaduke Sheild Fund and a Parke Davis Exchange fellowship. He conducted his PhD in Cambridge between 2013 and 2017, funded by the MRC, Pinsent Darwin Trust, and CHESS (Cambridge Home and EU Scholarship Scheme) studying the effects of oxytocin and testosterone administration on resting state and task neural activation in the typical and autistic brain.
Summary: During the talk I will be presenting our current work on integrating brain imaging and transcriptomic data in autism. I will also talk about our recent work to implement more individualised approaches to imaging analysis, specifically I will be presenting work on age-specific normalised modelling and integrative network analysis on structural brain imaging.
Bethlehem, R.A.I., Seidlitz, J., Romero-Garcia, R. & Lombardo, M.V. Using normative age modelling to isolate subsets of individuals with autism expressing highly age-atypical cortical thickness features. (bioRxiv: https://doi.org/10.1101/252593).
Romero-Garcia, R., Warrier, V., Bullmore, E.T., Baron-Cohen, S. & Bethlehem, R.A.I. (2018). Synaptic and transcriptionally downregulated genes are associated with cortical thickness differences in children with autism. Molecular Psychiatry,https://doi.org/10.1038/s41380-018-0023-7
Bethlehem, R.A.I., Romero-Garcia, R., Mak, E., Bullmore, E.T. & Baron-Cohen S. (2017). Structural covariance networks in children with autism or ADHD. Cereb. Cortex 27 (8): 4267-4276. https://doi.org/10.1093/cercor/bhx135
This event is generously funded by an MNI-Cambridge team grant.
Boris Bernhardt, PhD
Assistant Professor of Neurology and Neurosurgery
Montreal Neurological Institute and Hospital
McConnell Brain Imaging Centre